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yloI [2019-08-01 11:07:28]
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yloI [2019-08-01 11:07:28]

Coenzyme A biosynthesis bifunctional protein CoaBC; putative phosphopantothenoylcysteine synthetase/decarboxylase
Locus
BSU_15700
Isoelectric point
6.01
Molecular weight
43.82 kDa
Protein length
406 aa Sequence Blast
Gene length
1221 bp Sequence Blast
Function
biosynthesis of coenzyme A
Product
putative phosphopantothenoylcysteine synthetase/decarboxylase
Essential
yes
E.C.
4.1.1.36
Synonyms
coaBC
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Biosynthesis of cofactors → Biosynthesis of coenzyme A
  • Groups of genes → Essential genes

    • Gene

    Coordinates
    1,642,851 1,644,071

    Phenotypes of a mutant

  • essential PubMed

    • The protein

    Protein family

  • N-terminal part: HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily (single member, according to UniProt)
  • C-terminal part: PPC synthetase family (single member, according to UniProt)

    • Structure

  • 1U7U (from E. coli, 41% identity in 53% fragment) PubMed

    • Expression and Regulation

    Operons

    Genes
    yloC-remA-gmk-yloH-yloI-priA-defA-fmt-yloM-yloN

    Description

  • PubMed
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    Biological materials

    Mutant

  • MGNA-B372 (yloI::erm), available at the NBRP B. subtilis, Japan

    • References

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